Obesity and Alzheimer's Disease: Cognitive Decline and Risk

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Increased Risk: Obesity is associated with a higher risk of developing Alzheimer's disease, a progressive neurodegenerative disorder.

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Inflammation Connection: Obesity contributes to chronic inflammation, which may exacerbate the pathological processes involved in Alzheimer's disease.

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Insulin Resistance: Obesity often leads to insulin resistance, and this metabolic dysfunction may have links to cognitive decline and Alzheimer's risk.

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Vascular Impact: Obesity is a risk factor for vascular problems, compromising blood flow to the brain and contributing to cognitive impairment.

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Hormonal Imbalances: Adipose tissue in obese individuals produces hormones that may adversely affect brain function and increase Alzheimer's risk.

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Apoptosis and Oxidative Stress: Obesity-related factors can trigger neuronal apoptosis and oxidative stress, mechanisms implicated in Alzheimer's pathology.

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Reduced Brain Volume: Obesity may be associated with a reduction in brain volume, particularly in regions crucial for memory and cognitive function.

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Lifestyle Factors: Unhealthy lifestyle habits associated with obesity, such as poor diet and sedentary behavior, further contribute to cognitive decline and Alzheimer's risk.

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